The Garment District is a mostly commercial neighborhood in midtown Manhattan. It was once the epicenter of the fashion industry for the United States and many fashion and fashion supply companies are still based here. The core of the neighborhood tends to quiet down after working hours as commuters head home. There are some apartment and condo towers in the neighborhood — for the most part located near its western boundaries and closer to the amenities of Hell's Kitchen.
It is directly next to Times Square, which draws hordes of tourists, so this is not a low key area. Bryant Park and the beautiful New York Public Library are just a few minutes' walk away when you want some quiet time.
Wall Street: 5.5 miles / 15-35 minutes by car / 25 minutes by transit
Rockefeller Center: 1 mile / 5-15 minutes by car / 15 minutes by transit / 20 minutes by foot
Jersey City: 8.5 miles / 25-55 minutes by car / 35 minutes by transit